IN VIVO SILAC-BASED PROTEOMICS REVEALS PHOSPHOPROTEOME CHANGES DURING MOUSE SKIN CARCINOGENESIS



Effect of dietary carbohydrate on glycometabolism of juvenile golden pompano (Trachinotus ovatus) related to growth performance, hepatic histopathology, transcriptome profiles and identification of differentially expressed genes

A hepatic transcriptome was produced through the technology of RNA sequencing and short-read assembly in golden pompano Trachinotus ovatus fed with three experimental diets respectively containing low carbohydrate diet (LCD), intermediate carbohydrate diet (MCD), and high carbohydrate diet (HCD).In total, 57,217 unigenes were acquired in the curren

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Mycoviruses in the Rust Fungus Uromyces fabae

Uromyces fabae, the causal agent of broad bean rust, is a major cause of yield losses in North and East Africa, China, and Australia.It has also served as an important model species for research on rust fungi.Early EST sequencing in U.fabae showed that viruses might be present in this species; however, no follow-up investigations were conducted.In

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Transcriptome profiling identifies genes and pathways deregulated upon floxuridine treatment in colorectal cancer cells harboring GOF mutant p53

Mutation navy blue lantern in TP53 is a common genetic alteration in human cancers.Certain tumor associated p53 missense mutants acquire gain-of-function (GOF) properties and confer oncogenic phenotypes including enhanced chemoresistance.The colorectal cancers (CRC) harboring mutant p53 are generally aggressive in nature and difficult to treat.To i

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